International Research and Academic scholar society

IRASS Journal of Applied Medical and Pharmaceutical Sciences

Issue-8(August), Volume-3 2026

1. Effect of dietary organic selenium supplementation on some semen quali...
3

Nashwan Majeed Ali Al-Gburi*
DNA Research Center, University of Babylon, Hillah-Najaf Street, Babylon state, 51001, Iraq
1-5
https://doi.org/10.5281/zenodo.21980440

Reduced reproductive efficiency in Local Iraqi roosters is one of the primary challenges facing local poultry breeding flocks. This decline can be attributed to several factors, most notably nutritional imbalances and suboptimal management, alongside the deterioration of physiological and reproductive performance, the present study aimed to investigate the effects of selenium—a trace element known for its broad physiological impact—and evaluate its efficacy as a dietary supplement on the semen quality parameters of roosters. A total of 80 roosters, 22 weeks of age, were utilized in this study. The birds were randomly assigned to four treatment groups (20 roosters per treatment), with two replicates per treatment (10 roosters per replicate), The roosters were fed a nutritionally balanced basal diet supplemented with selenium from the onset of the study, All birds underwent continuous training for semen collection to ensure acclimatization to the procedure, Semen was collected bi-weekly throughout the 3-month experimental period, and mean values for each trait were calculated monthly for data presentation, The study evaluated various seminal characteristics, including ejaculate volume, mass activity, individual sperm motility, sperm concentration, packed sperm volume (PSV), and the percentages of dead and abnormal spermatozoa. The results of the current study indicated that selenium supplementation exerted effects ranging from significant to highly significant (P < 0.05and P < 0.01) across all studied traits throughout the experimental period. These findings suggest that selenium serves as a safe and effective nutritional tool for enhancing the reproductive efficiency of roosters, thereby opening new horizons for future research into utilizing the semen of these roosters for experimental insemination and fertility efficiency testing.

2. The Gut Microbiome as a Metabolic Organ: Biochemical and Nutritional E...
3

Udoeyop Favor1, Okorie Claribel1, Nweje-Anyalowu Paul2, Enyinnaya Blessing Oluchi3, Auwal Shehu Ali4, Banwo Faridah Mobolanle5, Shehu Muhammad Hassan6, Abdullahi Muhammad7, Usman Ibrahim8, Idakwoji Precious Adejoh*9
1Department of Medical Biochemistry, College of Medicine, Godfrey Okoye University, Ugwuomu-Nike, Enugu State, Nigeria., 2Biochemistry Programme, Department of Chemical Sciences, Faculty of Science, Clifford University, Owerrinta (Ihie campus), Abia State, Nigeria., 3Department of Public Health, Faculty of Basic Medical Sciences, Clifford University, Owerrinta, Abia State, Nigeria, 4Federal Teaching Hospital. Katsina, Katsina State, Nigeria., 5Department of Zoology, Faculty of Science, Ahmadu Bello University, Zaria, Kaduna State, Nigeria, 6Department of Biochemistry, Faculty of Life Sciences, Ahmadu Belo University, Zaria, Kaduna State, Nigeria., 7Ahmadu Belo University Distance Learning Centre and International Medical Corps, Zaria, Kaduna State, Nigeria., 8Department of Biotechnology, Modibbo Adamawa University, Yola, Adamawa State, Nigeria., 9*Department of Biochemistry, Faculty of Natural Sciences, Prince Abubakar Audu University, Anyigba, Kogi State, Nigeria
6-14
https://doi.org/10.5281/zenodo.22206897

Background: The gut microbiome functions as a dynamic metabolic system that interacts continuously with host nutrition and physiology, influencing energy balance, immune function, and disease risk. Objective: This review examines the gut microbiome as a metabolic organ, focusing on biochemical and nutritional evidence linking microbial activity to human health and disease. Methods: A narrative review approach was considered, integrating recent peer-reviewed literature on host–microbiome metabolic interactions, dietary modulation of gut microbial composition, and microbial metabolite signaling pathways. Results: Evidence indicates that gut microbes contribute to host metabolism through fermentation of dietary fibers into short-chain fatty acids, transformation of bile acids, and metabolism of amino acids and polyphenols. These microbial products act as signaling molecules influencing glucose homeostasis, lipid metabolism, inflammatory pathways, and gut barrier integrity. Dysbiosis has been associated with metabolic disorders including obesity, type 2 diabetes, non-alcoholic fatty liver disease, and cardiovascular disease. Dietary patterns rich in fiber and plant-derived compounds are consistently linked with beneficial microbial profiles and improved metabolic outcomes. Conclusion: The gut microbiome operates as a metabolically active organ that integrates dietary inputs with host biochemical pathways. Understanding these interactions provides a basis for nutritional strategies aimed at preventing and managing metabolic diseases.





Submit Manuscript